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...drugs provided relief to 60% to 80% of patients, but they also caused serious side effects, including sluggishness, weight gain and occasionally death from overdose. The ground was ripe for a better pill, and it wasn't long before scientists produced a new, highly targeted class of antidepressants, led by Prozac, which hit the U.S. market in 1987, followed by Zoloft in 1991 and Paxil in 1992. Instead of blanketing a broad range of brain chemicals, the drugs - known as selective serotonin reuptake inhibitors (SSRIs) - zeroed in on one: serotonin, a critical compound that ferries signals between nerve cells. SSRIs...

Author: /time Magazine | Title: Antidepressants | 1/7/2010 | See Source »

Fermi Wong had her moment of revelation one day in 1998. The social worker was roving the streets of a working-class neighborhood in Hong Kong's Kowloon district, looking out for truant youth, when she came across a gaggle of Pakistani kids playing soccer. They ran and tackled each other along the edge of a pavement, in view of an unoccupied public field equipped with proper goals. Bemused, Wong asked them why they weren't using the actual soccer pitch, which was open to all. "People told us we're not allowed there," came the response...

Author: /time Magazine | Title: The Racism Fighter | 1/6/2010 | See Source »

...first time in 25 years of traveling. But Peter Gruder said that two security checkpoints failed to find an oversize bottle of liquid that a checkpoint of German guards in Munich had found and allowed him to keep. Tony Williams, an American arriving from Qatar, said flying first class had put him in an expedited lane through security after connecting from an airport in Laos with "shockingly low security...

Author: /time Magazine | Title: International Flyers Report Extra Security, More Delays | 1/6/2010 | See Source »

Over the past two decades Mexico City has emerged as a player in the international contemporary-art scene, with a clutch of world-class artists, cutting-edge galleries and deep-pocketed collectors - of which juice tycoon Eugenio Lopez is the most important. Located at his family's sprawling Jumex juice factory just outside the capital, Lopez's Colección Jumex is a priceless assemblage of works by blue-chip local and international artists ranging from Gabriel Orozco to Andy Warhol. It is unequaled in Latin America...

Author: /time Magazine | Title: Mexico City's Jumex Art Collection | 1/6/2010 | See Source »

Some state courts have found that laws forbidding gay marriage achieve no legitimate interest at all. And others have ruled that while same-sex marriage bans may be rational, they can't survive a higher scrutiny that courts reserve for special classes of citizens - such as racial minorities and, on a more limited basis, women. No federal appeals court has so far held that gays and lesbians as a class are entitled to the special protection that requires heightened scrutiny of laws that discriminate on the basis of race or religion, for example. That may sound like a fine legal...

Author: /time Magazine | Title: A Gay-Marriage Lawsuit Dares to Make Its Case | 1/5/2010 | See Source »

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