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None of this is the stuff of functioning adulthood, but all of it is huge for a person who was never supposed to manage anything like it again. And all of it is a result of the growing therapeutic science of deep-brain stimulation (DBS). Doctors at the Cleveland Clinic inserted a pair of fine wires into the mugging victim's brain last year, threading them down to the thalamus, a deep, intact structure that could, in theory, jump- start the surviving circuits in the damaged cerebral cortex above. Very low current was sent through the wires, stimulating the thalamus...

Author: /time Magazine | Title: Rewiring the Brain | 8/30/2007 | See Source »

...Administration (FDA) approval for obsessive-compulsive disorder (OCD) and is in clinical trials as a therapy for depression. Studies suggest it could also help control symptoms of Alzheimer's disease, dystonia--or paralytic muscle rigidity--epilepsy and even some addictions. "DBS is like a pacemaker for the brain," says Cleveland Clinic neurosurgeon Ali Rezai, who performed the operation on the brain-damaged man. "We pinpoint the part that needs stimulation and provide...

Author: /time Magazine | Title: Rewiring the Brain | 8/30/2007 | See Source »

...something that counts as brain surgery, a DBS procedure can be a surprisingly relaxed thing. On a recent morning in Cleveland, Scott Stipp, 55, a businessman and Parkinson's patient, lies lightly sedated on an operating table while Rezai and a team of surgeons drill a hole about as large as a dime in the crown of his head. Rezai then threads a wire just 4 microns thick--or four-thousandths of a millimeter--into Stipp's brain. Guided in part by CT scans and in part by real-time readings of electrical activity that the probe encounters...

Author: /time Magazine | Title: Rewiring the Brain | 8/30/2007 | See Source »

...ongoing controversy may have impacted Lucy's future travel plans as well. Additional venues for her tour have yet to be announced and at least two prominent institutions - the natural history museums in Washington and Cleveland - have refused to host the exhibit. Meanwhile, in 2008 the National Museum in Ethiopia plans to inaugurate a new building dedicated to research, conservation and storage of antiquities, including fossils - but its star attraction won't be there...

Author: /time Magazine | Title: The Hassles of Having Lucy in Houston | 8/24/2007 | See Source »

DENVER IS JUST ONE PIN ON THE NATIONAL map. Looking across the country, the foreclosure problem is worst in areas where house prices went wildest (southern Florida, California), where local economies are depressed (Cleveland, Detroit) and where regulators paid little attention during the go-go years (before a new law took effect in January, mortgage brokers in Colorado didn't have to be registered). But it is important to point out that while Colorado has one of the nation's highest foreclosure rates, according to property tracker RealtyTrac, many parts are doing just fine. Prices in Denver's newly...

Author: /time Magazine | Title: Ground Zero of the Real Estate Bust | 8/16/2007 | See Source »

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