Word: clinicals
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...blood-fats arm of the ACCORD study, for instance, about 40% of the volunteers had already had a previous heart event and the remainder had risk factors, other than diabetes, that put them at high risk for heart disease, notes Dr. Om Ganda, director of the lipid clinic at Joslin Diabetes Center in Boston. That means the trial was not truly a primary-prevention study designed to test whether aggressive drug treatment could prevent a first heart attack in newly diagnosed diabetes patients...
...judges determine whether or not it is even a judicial decision to close a clinic?” she said. “Perhaps that is a legislative issue...
...year Dorchester resident, who is currently unemployed, first stopped by the Harvard Medical School-affiliated mobile health clinic four years ago out of curiosity...
Whether the findings are sufficient to translate to the clinic, though, is another matter. Some experts are not convinced - yet - that the study results should be part of clinical decisionmaking, pointing out that many factors other than mastectomy may be driving the increase in survival. "Women who undergo a [preventive] mastectomy in the unaffected breast may be different from women who do not," says Dr. George Sledge, president-elect of the American Society of Clinical Oncology and a professor of medicine at Indiana University. "They may be overall healthier in that they see their physician more frequently, and their physicians...
...Larry Norton, a breast-cancer expert at Memorial Sloan-Kettering Cancer Center in New York City, agrees and cautions against applying these findings immediately to the clinic. "This is an observational study, and hence it is impossible to control for confounding variables," he says, "and should not be used for individual clinical decisionmaking." But Norton acknowledges that the ideal study - in which women would be randomly assigned to either have a double mastectomy or not - could never be done, since it would not be ethical to prevent women from having a procedure known to reduce the risk of cancer recurrence...