Word: clinicals
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...Proceedings of the National Academy of Sciences, researchers at Arizona State University's Biodesign Institute, the University of Arizona and the Mayo Clinic in Arizona report a very small study of nine individuals - three of normal weight, three who were morbidly obese and three who underwent gastric-bypass surgery. The team found that each group harbored a different intestinal zoo of microbes and that following their surgery, the gastric-bypass patients' gut bugs ended up looking much more similar to those of the normal-weight patients. (See the Year in Health, from...
...that doctors and patients might be able to tackle the growing obesity epidemic in the U.S. "This study suggests that the differences in the organisms may play at least some role in why people lose the weight they do," says Dr. John DiBaise, a gastroenterologist at the Mayo Clinic and one of the study's authors. "Ultimately, we may not only be able to manipulate the microbes of obese individuals to look like those of normal-weight people, but we might also potentially be able to predict a person's susceptibility to obesity...
...study, the authors say, is the fact that all patients seeking infertility treatment in the state of Massachusetts are at least partially reimbursed by their health-insurance carriers, by law. IVF can cost up to $10,000 or more per cycle, and the study group at the Massachusetts clinic likely included many patients less deterred by financial issues than women in the general population, possibly distorting the data. Malizia, who now serves as a reproductive endocrinologist at Alabama Fertility Specialists in Birmingham, Ala., suggests, however, that the live-birth rates of her study group skewed lower than they might have...
...analysis of the overall live-birth rate for 6,164 patients at a Massachusetts fertility clinic, researchers from Boston IVF and Beth Israel Deaconness Medical Center found that in women ages 39 and younger who were treated with up to six cycles of IVF, the rate of live births ranged from 65% to 86%; in women ages 40 and older, the live-birth rate...
...study's more than 6,000 participants became pregnant and gave birth, or underwent the full six cycles of IVF before leaving the clinic, which accounts for the range of live-birth rates. Researchers had to extrapolate from their existing data the likely outcomes for patients who discontinued treatment: In the "optimistic" analysis, researchers assumed that the women who discontinued treatment would have had the same success rates as those who continued treatment; the "conservative" analysis assumes a zero success rate among all women who discontinued IVF at that particular clinic. Realistically, say the authors, the actual live-birth rates...