Word: clocking
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...worked in the lab of Molecular and Cellular Biology Professor Erin K. O’Shea for five semesters and two summers to prepare his thesis on temperature compensation in the three protein circadian clock...
Low’s research focuses on temperature compensation of the three-protein post-translational oscillator in the cyanobacterial biological clock. The oscillator controls global gene expression and regulates cyclical changes in the organism's physiology, biochemistry, and metabolism...
...used existing mathematical models of the biological clock developed by others to predict the effects of temperature changes on the in vitro clock. He then compare the predictions from the model to experimental data...
...surprise, the clock experienced no effect and ticked at a regular rate despite the changes...
...found that a majority of the rate constants in the oscillator are not temperature-sensitive, but a small number are—suggesting that the temperature compensation of period length may result from a more fundamental property of the clock. Low proposed that the small number of temperature-sensitive rate constants may play an integral role in entraining the clock to diurnal temperature cycles in the environment...