Word: clots
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Dates: during 1950-1959
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Arthur D. Schulte, son of the developer of the Schulte national chain of cigar stores, was making rapid strides in his father's footsteps when, at 32, he fell ill with thrombophlebitis-inflammation of leg veins, with formation of clots that could be fatal if they reached the lungs. That was 20 years ago. Schulte's physician, Dr. Irving Wright, casting around for a drug to prevent clot formation (none had yet been proved effective in man), appealed to Nobel Prizewinner Charles H. Best, co-discoverer of insulin. He wanted some of the heparin that University of Toronto...
From Rotten Clover. Heparin has had a distinguished history since Schulte's early case, has proved invaluable in a variety of conditions where clotting is a danger, notably after a patient has already had a heart attack or stroke from a thrombus (clot). Heparin's advantage over most rival anticlotting drugs: it acts immediately. Its disadvantages: it is expensive and must be injected under the skin or infused into a vein...
...more dismayed by the sensational stories than Dr. Mario Stefanini of Boston's St. Elizabeth's Hospital, who had worked for two years to get the extract (an enzyme) from common molds. He has found that it dissolves the fibrous part of clots in animals and has tested its safety in 25 humans. But it will be two years, he estimates, before its value in relieving the symptoms of heart attacks and strokes can be shown. In any case it cannot reverse the original damage done by the clot. There is no assurance that the extract...
...area gets its blood supply from one of the countless branches of the middle cerebral artery. The particular branch supplying Broca's area is not much thicker than the lead in a pencil, and if in Ike's case this was already narrowed by arteriosclerosis, a tiny clot would be enough to shut down the flow. That a bigger artery branch was not involved was shown by Ike's keeping full command of functions controlled by adjacent brain areas...
...President got, even in the first stages of his illness, was a mild sedative. Beyond that, he is expected to stay on anticoagulants. In the case of a mild stroke such as Ike's, recovery is apt to take place-barring a new stroke-simply because the clot has dissolved. Even in more serious cases, when brain cells are damaged or destroyed, partial recovery is possible, as neighboring brain cells take over the function of damaged cells and other blood vessels take over to supply the damaged area with blood...