Word: clots
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Dates: during 1980-1989
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...study finds that artery-inflating balloon angioplasty is unnecessary if a heart-attack patient is given a clot-dissolving drug. -- Snuffing the common cold...
...most heart-attack cases. The 50-hospital study, sponsored by the National Institutes of Health and known as TIMI II (for thrombolysis in myocardial infarction phase II trial), involved 3,262 patients who had suffered apparent heart attacks. Within four hours of their attacks, all patients received a powerful clot dissolver, known as TPA (tissue plasminogen activator), along with heparin and aspirin to inhibit blood coagulation. Of the 1,636 patients in the invasive-strategy group, 928 underwent angiography and angioplasty within 18 to 48 hours after their attacks...
...study excluded patients age 76 and over, as well as anyone with a history of bypass surgery, heart-valve replacement, cerebrovascular disease, or other serious illness. "These were low-risk people, and it's a bad rap for angioplasty," he complained. "In fact, direct angioplasty alone, with no clot-dissolving drugs, is probably the single most effective treatment for acute heart attack...
...excess of LDL, which normally carries some 60% to 80% of the blood's total cholesterol. This excess can trigger the formation of plaque on the interior walls of the coronary arteries, a condition called atherosclerosis. In time, this hardened, sludge-filled growth narrows the artery and allows a clot to form, severely blocking the blood flow. The result: a heart attack...
...weakening in an artery supplying blood to the brain; the artery was already leaking. Biden was rushed to Walter Reed Army Medical Center for eight hours of cranial surgery, which many patients do not survive. Lying completely still in intensive care afterward led to the development of a blood clot on his lung, which required an operation to implant a filter in a vein. In May he was back on the operating table, for surgery on a second aneurysm. It was a hellish time, but he is completely recovered. "The good news is that I can do anything...