Word: clotting
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...thought this was one of the best debates I’ve seen. The Republicans dealt with the issues substantively, and neither side tried to clot the debate with rhetoric,” Todd said. “This definitely made me more interested in getting involved...
Using information technology to figure out which treatments are most effective seems eminently sensible. Certain heart patients, for example, do just as well with clot-busting drugs as they would with angioplasty procedures, which typically cost thousands more. Crunching huge amounts of data from a wide cross section of patients could help us do better research than we are doing now. But what will happen when the new computerized research turns up a treatment that works a little better but costs a lot more? Will the government-sponsored researchers tell us? What happens to the patient whose particular circumstances argue...
...make you feel better and live longer; those are the patient outcomes. Sometimes though, good surrogate outcomes don't lead to good patient outcomes. Hormone replacement therapy, for example, raises good cholesterol, which helps reduce the risk heart disease. But it also makes the blood more likely to clot, which raises the heart disease risk. A cancer treatment that shrinks the size of a tumor is of limited value if it's soon followed by tumor regrowth...
Finally, the political debate also revolves around using information technology to figure out which treatments are most effective. This seems eminently sensible: might certain heart patients, for example, do just as well with clot-busting drugs as with more expensive angioplasty procedures? The drug route could save about $7000 a patient Crunching huge amounts of data from a wide cross section of patients could help us do better research than we are doing now. But what will happen when the new computerized research turns up a treatment that works a little better but costs much more? Will they tell...
...fatigued, she never betrays it. An eager, insistent clot of people pushes toward her, and somehow she manages to greet each well-wisher with a fractional recalibration of body language that suggests a wordless surge of elated surprise on her part: Oh, it's you! You're the one I've been most hoping to see, and how wonderful that we share that secret knowledge! To achieve this effect, Winslet must appear, at every minute, to be not only the most interesting person in the room but also the most interested. This is not easy, and she does it very...