Word: cmf
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...undergone mastectomies. From tissue samples physicians found that three-quarters of the women had estrogen-linked tumors. These patients, as well as the others whose cancers were not connected with the hormone, were divided into three treatment groups: one was given a combination of drugs known as CMF; another CMF and tamoxifen; and the third CMF, tamoxifen and BCG (which is designed to bolster the immune system...
...estrogen group, the relapse rate was 40% in those treated with CMF alone. But, remarkably, among women who had also been given tamoxifen, cancer reappeared in only about 10% of the cases...
...Istituto Nazionale Tumori, the Italian equivalent of the U.S. National Cancer Institute (which supported the study). Led by Dr. Gianni Bonadonna, who studied at Manhattan's Memorial Sloan-Kettering Cancer Center in the 1960s, the Milan team picked three drugs-cyclo-phosphamide, methotrexate and 5-fluorouracil (CMF). All were known to interfere with the growth of cells, especially of fast-multiplying cancer cells. But they proved to be more active than when used alone...
Severe Side Effects. The CMF therapy lasted a year, during which the women alternately received doses of the drugs for two weeks, then went without them for two weeks to enable them to recover from the severe side effects. Besides nausea, vomiting, loss of hair and the cessation of menstruation, the drugs cause a decline in production of white blood cells, which are part of the body's defenses against infection. As the tests continued, however, most of these effects subsided and many of the women were , able to go back to work...
...hurdles were won, of course, by Hunter in 25.4 seconds with Petrolla, again, right behind him. Ed Lewis of Harvard came in third and Dahl of Rhode Island was in the fourth spot. Harvard came in third cmfw cmf spot. Clark hung up his second win in the 220, coming home in 23 seconds, not even bothering to climb out of his sweat suit for the event. Cameron was the number two man. Gilmartin of Holy Cross was the third and Kennett, of Rhode Island, fourth...
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