Word: cohn
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...dedication ceremonies a year ago Cohn pointed out that "neither alcohol, very low temperature, drying equipment, nor radiation equipment for virus sterilization is necessary" to produce Stable Plasma Protein Solution which, he believes, "will replace serum albumin, dry plasma, and wet plasma...
...Cohn was asked to investigate to determine whether animal plasma could be safe for human transfusion. New methods for the fraction of plasma were therefore rapidly developed during the spring and summer of 1940. Techniques to yield undenatured products of great stability resulted. These methods had been applied successfully on a large scale, and studies were available demonstrating the value of such products in the treatment of shock...
Before the end of the year, however, Cohn was convinced that the problem of freeing animal material of the possibility of antigenic reactions might prove insoluble, and that in any case, the animal plasma project could not be completed in a short time. He thus recommended that only human products be used...
Throughout World War II Cohn studied blood and blood derivatives under contract with the Office of Scientific Research and Development. Nationwide blood collection made possible the study and clinical use of human blood on a scale never previously conceivable. Donors' blood was supplied to the Pilot Plant week by week and the products of fractionation were studied and tested...
After the war there was a return to fundamental research, and out of it, in October 1950, Cohn came up with his first mobile blood fractionation plant that could go to the donors. It was housed in a 32-foot trailer-truck so this refrigerated lab could go along with Red Cross Bloodmibiles processing could start within a few moments after collection. By November the truck was rendered obsolete by the development of the newer methods...