Word: colestipol
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Dates: during 1980-1989
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...case. Last year Dr. David Blankenhorn, director of atherosclerosis research at the University of Southern California, reported on a study in which 162 nonsmoking men who had undergone coronary- bypass surgery were put on a low-fat diet; 80 of them were also treated with niacin and colestipol. Among the drug-treated group, HDL levels increased 37%, while LDL decreased 43% and triglycerides went down 22%. Blankenhorn found evidence that arterial disease had been halted in 61% of the drug- treated patients, compared with 39% who were treated by diet alone. Moreover, 16% of the drug-treated group, vs. only...
...prescription for lowering cholesterol levels still reads like a California cafe menu: low-fat milk and dairy products, lean meat, few eggs and absolutely no animal fat or poultry skin. If cholesterol cannot be reduced with diet alone, the panel directed, physicians should prescribe such drugs as cholestyramine and colestipol, which act in the intestines and cause the body to utilize excess cholesterol. The much touted newer drug lovastatin, which works in the liver, where most of the body's cholesterol is manufactured, is mentioned as a second choice, since its long-term effects remain unknown. Based...
...slow the growth of new blockages in the coronary vessels. ( But the proper treatment has proved elusive. Last week in the Journal of the American Medical Association, Dr. David Blankenhorn of the University of Southern California reported that patients who were treated with a combination of the anticholesterol drug colestipol and the vitamin niacin showed a marked improvement over those who had maintained a low-fat diet alone...
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