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Word: coli (lookup in dictionary) (lookup stats)
Dates: during 1990-1999
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Regardless of how Alpine's water tasted, there was in fact something grievously--perhaps lethally--wrong with it. That something was a particularly dangerous strain of the E. coli bacterium called E. coli O157:H7, or O157 for short. Ordinarily a benign organism found in the intestines of human beings and animals, E. coli has a nasty ability to mutate and proliferate. Lately it has been proliferating with a vengeance. Five years ago, the fast-food industry was rocked when four children died and 500 other people fell ill after eating E. coli O157-contaminated hamburgers at Jack...

Author: /time Magazine | Title: Anatomy Of An Outbreak | 8/3/1998 | See Source »

...problem indeed. Of all the bacteria that bloom in the body, E. coli is usually one of the most beneficial, helping to metabolize food in the intestine. In 1982, however, scientists discovered that E. coli wasn't always so benign. That year 26 people in Oregon were felled by a violent infection and intestinal disorder, and when doctors analyzed the bug behind the illness, they found that it was all but indistinguishable from ordinary E. coli, with but a small exception: this breed of the bacterium contained a few strands of genetic reweaving that cause it to produce a powerful...

Author: /time Magazine | Title: Anatomy Of An Outbreak | 8/3/1998 | See Source »

When this fortified E. coli, which researchers dubbed the O157:H7 strain, takes hold in the body, it behaves savagely. Doctors believe the bacterial toxin first destroys blood vessels in the intestines, which accounts for the bloody diarrhea that is the signature symptom of the infection. The toxin then passes into the bloodstream, where it probably damages vessels throughout the body. This produces gummy clots that clog organs like the kidneys. Up to 5% of all people with O157 infection develop a kidney condition known as hemolytic uremic syndrome; up to 5% of all HUS cases are fatal. The clotting...

Author: /time Magazine | Title: Anatomy Of An Outbreak | 8/3/1998 | See Source »

Certainly, O157 E. coli is not an easy bug to pick up. It's not an airborne pathogen like a flu virus, and it can have an ill effect only if it's ingested. The vast majority of people who do come down with the infection survive if they are kept hydrated and, in some cases, hospitalized. But up to 1% do die--mostly children, the elderly and people with compromised immune systems. In all cases, antibiotics are not only useless but may actually make things worse, causing the bacteria to rupture and spill their toxin even more widely throughout...

Author: /time Magazine | Title: Anatomy Of An Outbreak | 8/3/1998 | See Source »

...COLI BEGONE! An experimental vaccine seems to prevent infection with the E.coli bacteria that cause food poisoning...

Author: /time Magazine | Title: Health Report: Feb. 23, 1998 | 2/23/1998 | See Source »

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