Word: coli
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...coli makes interferon
...only a starting point. After extracting messenger RNAs from human white blood cells, which were producing interferon, they used these molecules to generate sections of DNA that they hoped would include the required gene. They then spliced these fragments into the genes of a laboratory strain of E. coli bacteria. The bacteria began to make copies, or clones, of their altered selves...
...coli makes a vital hormone...
...Francisco and at a small commercial research firm, Genentech Inc., in nearby Palo Alto, used human pituitary tissue to construct the gene, or DNA segment, responsible for the production of somatotropin. They then implanted it in the genetic machinery of a laboratory strain of the common intestinal bacterium Escherichia coli. The gene splicing worked: the re-engineered bugs began to make...
Several obstacles must yet be overcome. Among them: getting the bacteria to produce pure HGH and testing the substance in living creatures, including man. Still, the scientists hope that within two years vats of genetically redesigned E. coli will be acting as minifactories, churning out sufficient somatotropin to treat dwarfism. There may also be enough to test a long held suspicion: that HGH can help heal burns, wounds, bone fractures and even bleeding ulcers...