Word: coli
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...molecule of life, might accidentally lead to the creation of new, uncontrollable strains of disease-carrying bacteria. Now most experts have decided they greatly overstated the dangers. But many laymen have remained frightened ever since research at Harvard designed to create new combinations of DNA in the bacterium Escherichia coli K12, or E. coli for short, stirred passionate debate last year (TIME cover, April 18). Last week, after long hearings, Congress was scheduled to act on two bills seeking to control such research. The rush to adjourn forced a postponement of action until after the summer recess, but the issue...
Experiments with the lowly E. coli bacterium hold a promise of many marvels, including food crops that require little fertilizer and the production of new tools for the understanding of disease, perhaps including cancer. Pursuing such research, biologists are naturally loath to become ensnared in more Government regulations. They point out that governmental regulation poses inherent dangers to the freedom of inquiry that science requires. Comments Biochemist Robert White of the National Academy of Sciences: "I hate to see the camel's nose under the tent...
...open the U.S. pavilion at the show, gallantly passed his ceremonial scissors to Mrs. Lindbergh. French President Valéry Giscard d'Estaing also paid his respects. Mrs. Lindbergh won over everyone with a graceful tribute to pioneering French aviators, including Charles Nungesser and François Coli, who disappeared at sea on a transatlantic flight in 1927. Said she: "It takes as much courage to have tried and failed as it does to have tried and succeeded...
...reason and because of the increasing demand for the hormone, which the body needs to turn sugar into energy, drug companies seeking alternative sources have pinned some of their hopes on recombinant DNA technology. By inserting the human insulin gene into the DNA of the common intestinal bacterium Escherichia coli, they could, in theory, endow the bug with the capacity to make human insulin...
...achievement announced last week, Biochemists Howard Goodman and William Rutter and their colleagues did not work with human genes. Under the safety guidelines adopted by the National Institutes of Health (to lessen the risk of accidentally producing an E. coli that might be harmful), such less readily available material would have required a far more stringent level of physical containment in the lab than any yet available. Instead, they experimented with insulin genes from rats. Placing this foreign DNA inside enfeebled E. coli, they were delighted to find that the genetic material was replicated every time the bacteria divided...