Word: colonization
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Dates: during 1980-1989
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That the patients were only laboratory mice did not detract from the results: 100% cured of colon cancer that had spread to the liver, 50% cured of colon cancer spread to the lungs. These are remarkable cure rates for malignancies that are virtual death sentences for both mice and people. The encouraging results were announced last week by a researcher of near celebrity status, Dr. Steven Rosenberg of the National Cancer Institute. It was Rosenberg who, as spokesman for the team of doctors performing colon surgery on Ronald Reagan, shocked the nation last year by announcing on television, "The President...
...treatments. As a result, few serious side effects were apparent. With the addition of cyclophosphamide, a drug that Rosenberg believes suppresses immune-system cells that might otherwise impede the TIL cells, the treatment achieved its spectacular success rates. Most important, the combined therapy cured mice of advanced colon cancers that in parallel animal experiments had withstood the LAK cells. Can TIL immunotherapy work in humans? "There are some questions," says Dr. Alexander Fefer, a University of Washington researcher who has pioneered in the development of T cells that target malignancies. Perhaps the most significant question is whether human TIL cells...
During her teens, Maria Menna Perper, 42, a New Jersey biochemist, suffered intestinal problems around the time of her period. By her late 30s, she felt "excruciating, burning pain" in her colon every month "like clockwork." Eventually the pain became continuous, and it was impossible for her to work or even sit down...
...editor of Time Inc.'s DISCOVER magazine, he returned to TIME last year to take overall editorial responsibility for the Science, Medicine, Space, Environment and Computers sections. In the ensuing months he has found time to write several stories, including articles on the medical ramifications of President Reagan's colon surgery last summer and on the strange behavior of the star Sirius last November...
Bethesda Naval is the hospital of Presidents. Ronald Reagan went there last year to have a cancerous polyp removed from his colon. Richard Nixon was treated for viral pneumonia at the 500-bed facility in 1973. Lyndon Johnson had his gall bladder excised at the hospital in 1965 then proudly displayed his scar to anyone who cared to see it. Bethesda, in the northwest outskirts of Washington, D.C., is also a jewel in the crown of the U.S. military health care system, whose 688 facilities care for the nation's wounded in time of war. But presidential patronage notwithstanding...