Word: colonizers
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Folkman said that the next step includes testing the effectiveness of Avastin on forms of cancer other than colon cancer and on patients receiving various doses of chemotherapy...
...these rare cases, side effects might include the formation of holes in the colon. Such side-effects would require surgery to prevent intra-abdominal infections or internal bleeding...
...Aspirin. A well-known inflammation fighter, aspirin can cool reactions raging in heart arteries and in the colon. Similar agents are also showing promise in controlling inflammation in the brains of Alzheimer's patients...
...should you be taking Celebrex to prevent colon cancer? It's still too early to say. Clearly COX-2 is one of the factors in colon cancer. "But I don't think it's the exclusive answer," says Ray DuBois, director of cancer prevention at the Vanderbilt-Ingram Cancer Center in Nashville, Tenn. "There are a lot of other components that need to be explored...
That may soon change. Researchers are looking beyond aspirin and other multipurpose medications to experimental drugs that block inflammation more precisely. Any day now, Genentech is expecting a decision from the FDA on its colon-cancer drug, Avastin, which targets one of the growth factors released by the body as inflammation gives way to healing. Millennium Pharmaceuticals is testing a different kind of drug, called Velcade, which has already been approved for treating multiple myeloma, against lung cancer and other malignancies. But there is a sense that much more basic research into the nature of inflammation needs to be done...