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...promising weapon against leukemia-but not a cure. The enzyme, which apparently starves cancer cells of nutrients that they cannot manufacture themselves, is extracted at great cost-about $15,000 for a month's treatment for an adult-from growths of common bacteria found in the human colon. Dr. Hill is still enthusiastic about the drug and will soon have an abundant supply of it for further trial. Milwaukee's Miller Brewing Co. is closing down part of a Fort Worth brewery and donating fermentation equipment for enzyme production to Wadley's research institute. With the brewery...

Author: /time Magazine | Title: Cancer: Enzyme v. Leukemia | 7/7/1967 | See Source »

...birthday party for a nonagenarian Texas oil millionaire is an unlikely occasion for the announcement of a new treatment that may be effective against some forms of cancer. No less unlikely, as a source of the promising substance, are common colon bacteria that multi ply in sewage and often result in the contamination and closing of beaches. Yet both these elements were present last week in the excitement over a procedure that has given signs of success in the case of just one cancer parent...

Author: /time Magazine | Title: Cancer: Secret from the Guinea Pigs | 4/14/1967 | See Source »

...asparaginase is its scarcity. If all Texas were turned into a giant guinea-pig farm, the yield would suffice for only a few patients. The break came in 1963, when researchers at the University of Delaware described an immensely complicated process for extracting the enzyme from colon bacilli, Escherichia coli. These bacteria were already being grown in vats to provide other substances used by biochemists, and New Jersey's Worthington Biochemical Corp, set about extracting L-asparaginase from them. It takes pounds of the microscopic bacteria, and would cost close to $15,000, to produce enough L-asparaginase...

Author: /time Magazine | Title: Cancer: Secret from the Guinea Pigs | 4/14/1967 | See Source »

...nourished for days until they grow large enough for the disease-causing microbes to be detectable. The careful placing and size of an electrical charge is the key to Peri-Start, a machine built on the principle of the cardiac pacemaker. It electronically stimulates the muscles of bladder and colon and controls elimination in a paralyzed patient. In the future, the same technique may well prove practical for other muscles...

Author: /time Magazine | Title: Instrumentation: The Machines of Progress | 10/7/1966 | See Source »

...Loop. Dr. Troncelliti opened the man's abdomen and cut the small bowel about 42 inches below the point where it emerges from behind the large bowel (see diagram). He took the free end of this 42-inch loop and stitched it into the side of the transverse colon, leaving the remaining 15 to 20 feet of the small bowel as a nonfunctioning blind loop. When the man recovered from the operation, he continued to overeat, but the food digested in his stomach and duodenum passed more directly into his colon. He absorbed enough protein and starch to keep...

Author: /time Magazine | Title: Surgery: Bypassing the Small Bowel | 10/29/1965 | See Source »

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