Word: colonizes
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...with what it can do. Not only does this cheap, century-old drug (derived originally from the bark of the willow tree) relieve pain and ward off heart attacks, but now there is also strong evidence that it is one of the few compounds that offer real protection against colon cancer, the second leading cause of death from cancer in the U.S. The results of two studies published in last week's New England Journal of Medicine clearly show that taking aspirin every day--in low or high doses--reduces the number and size of polyps, the small precancerous growths...
...this mean that everybody should start taking daily doses of aspirin? Not necessarily. Aspirin, after all, carries its own risks, including internal bleeding, stomach ulcers, allergies and in rare cases strokes. The patients in these two studies were selected because they were known to be at high risk for colon cancer--which tended to tip the risk-benefit ratio in their favor. Whether daily aspirin use makes sense for the rest of us is still not clear...
...role in spurring cell growth that can lead to tumors. But for reasons no one can yet explain, higher doses of aspirin didn't translate into more protection. In one of the studies reported last week, more patients in the group taking full-strength, 325-mg aspirin pills developed colon cancer (10.7%) than in the group taking so-called baby, or 81-mg, aspirin (7.7%). The cancer rate in the placebo group, by contrast...
...reason to suspect that other anti-inflammatory drugs, such as Advil and Motrin or the newer COX-2 inhibitors Vioxx and Celebrex, might offer similar protection, only aspirin has been rigorously tested. Tylenol (acetaminophen) is not an anti-inflammatory, so don't expect it to protect you against colon or any other cancer...
...sequencing effort was just a starting point for much more science. He said an immediate target should be reducing the cost of sequencing an individual genome to $1,000 or less in the next decode or so. This would be a powerful tool, he said, to catch diseases like colon cancer years before the onset of observable symptoms when there is a 90 percent or better chance of curing them. "We would give power to the individual to know their own risk of disease," he said...