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...hoping it won't come to that. He is not under any illusion that a successful antibody-based treatment will have the sweeping effect of the polio or measles or smallpox vaccines - essentially wiping out the diseases in treated populations. Instead, an ibalizumab-based therapy will be just one of many weapons against HIV, albeit a very powerful one. "At our first meeting on this, I said I have a strategy that I feel will work," Ho recalls. "It was truly my gut feeling...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

...Washington; it's just that he was finding, as every President finds, that many of them lose their minds. House Speaker Sam Rayburn warned him about it: "Sycophants will stand in the rain a week to see you and will treat you like a king," he said. "They'll come sliding in and tell you you're the greatest man alive - but you know and I know...

Author: /time Magazine | Title: Obama After One Year: The Loneliest Job | 1/25/2010 | See Source »

...real loneliness of the office does not come from old friends preening and new ones pretending. It comes from the nature of the job. Dwight D. Eisenhower recalled how as a general, before D-Day, he had to decide whether to send two paratroop divisions into a sector where 9 out of 10 would probably be slaughtered. He eventually decided the troops were essential to the mission, and for years after that, he said, "I felt that only once in a lifetime could a problem of that sort weigh as heavily on a man's mind and heart." Then...

Author: /time Magazine | Title: Obama After One Year: The Loneliest Job | 1/25/2010 | See Source »

...year ago at his Inauguration, Obama affirmed that "we come to proclaim an end to the petty grievances and false promises, the recriminations and worn-out dogmas that for far too long have strangled our politics." Maybe it's the memory of those huge, happy crowds that makes the contrast between then and now so irresistible. OBAMA WALKS A LONG AND LONELY ROAD, observed a recent headline in the Financial Times, and that image is everywhere - a once untouchably popular figure unable to connect as President the way he did as a candidate or shine the light of hope...

Author: /time Magazine | Title: Obama After One Year: The Loneliest Job | 1/25/2010 | See Source »

...raise an important and serious issue and then create a movie answer for it--something that can solve the problem in under two hours. Neither am I interested in being a poster boy for a cause. We shouldn't decide which side of the issue we come down on on the basis of what celebrity we want to ally with...

Author: /time Magazine | Title: 10 Questions for Harrison Ford | 1/25/2010 | See Source »

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