Word: compounded
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...gene defect results in a protein that does not function, says Myriad's Skolnick, "you would try to replace that function by introducing a correct version of the protein into the body. Or you would try to mimic the function of the missing protein with a synthetic compound...
Virtually all anticancer drugs interfere with cell division in some fashion. Cyclophosphamide, the compound that finally banished Dustin Fagan's cancer, belongs to a broad class of drugs that damage the DNA molecule by plastering it with sticky cross-links, thus triggering the suicide sequence. By contrast, the taxoids--including taxol, the compound isolated from the bark of the yew tree that was approved by the Food and Drug Administration as a weapon against ovarian cancer in 1992--cause the same suicidal result by deactivating a molecular machine that, just before cell division, separates the DNA in each chromosome into...
...ingredient is a naturally occurring chemical found in pine trees--something else Finland has a lot of. Called sitostanol, the compound makes it harder for the body to absorb cholesterol. One of Raisio's scientists figured out how to extract sitostanol and mix it with conventional margarine. Then doctors from Helsinki tested the blend for a year on 153 subjects and reported in the prestigious New England Journal of Medicine that the cholesterol counts of people who used sitostanol-laced margarine daily dropped from 235 mg/dL to 210 mg/dL...
...called Freemen compound has been quietly put up for sale by the federal Farm Service Agency. Ralph Clark's 960-acre home, which he called Justus Township, was the site of the 81-day standoff that ended June 13. Clark, whose father acquired the property in 1926, quit making payments on his federal farm loans in 1982. Debt and interest on the place swelled to $2.5 million. Asking price for the Freemen headquarters: $150,000. But bargain-hunting land barons and roadside-attraction speculators can forget it: only "beginning farmers/ranchers" are eligible to apply for the screening process, the buyer...
...allies have plenty of company on the wide-ranging suspect list. Hizballah, the radical Lebanese organization, restricts its military operations to Israeli territory. But some U.S. officials suspect that Hizballah may now be seeking revenge against the U.S. for supporting Israel, even after its army shelled a United Nations compound in the Lebanese village of Qana last April, killing more than 100 civilians. Threats have also come from Egypt's Islamic Group, which has pledged to strike at the U.S. for imprisoning its spiritual leader, Sheik Omar Abdel Rahman. Rahman, a blind Egyptian cleric, was convicted last year of plotting...