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...Conn reasoned that a hormone must be at work, influencing especially the body's handling of salts. But nobody had identified a hormone with such precise effects. He could only guess that it was one of the many produced by the outer cortex or "bark" of the adrenal glands which are astride the kidneys. In the early 1950s, other investigators confirmed Conn's hunch by isolating an adrenal hormone now called aldosterone and recognized as one of the most powerful of all the body's chemicals...

Author: /time Magazine | Title: Endocrinology: Blood-Pressure Hormone | 3/15/1963 | See Source »

Into the Cure Column. First patient to get the benefit of Dr. Conn's aldosterone research was no tropic-bound G.I., but a 34-year-old Michigan woman whose high blood pressure (170 over 100) was accompanied by unusual features. She had muscular weakness and cramps, had to drink and urinate frequently; her low-salt sweat and abysmally low level of potassium in the blood indicated an excess of aldosterone. A medical team traced her trouble to a small tumor on her right adrenal gland, which was pumping out a flood of aldosterone although there was no excess...

Author: /time Magazine | Title: Endocrinology: Blood-Pressure Hormone | 3/15/1963 | See Source »

...many such patients there are." says Dr. Conn, "is anybody's guess." They run the gamut from those with strikingly severe symptoms to those detected only by chance chemical tests. And the picture is complicated because some victims of a rare, rapidly progressive and fatal form of high blood pressure develop an aldosterone excess apparently as an effect, rather than a cause, of their original disease. But whatever the statistics, the volunteers who pedaled themselves silly on Dr. Conn's exercise bicycles have a good deal to show for their sweat. At least 70% of aldosterone-tumor patients...

Author: /time Magazine | Title: Endocrinology: Blood-Pressure Hormone | 3/15/1963 | See Source »

Below the gossamer-thin plastic bag that climbed over Palestine, Texas, dangled a 6,300-lb. L-shaped package as bulky as two Cadillacs. It was surely one of the most ungainly-looking loads ever hefted aloft. Designed and built by PerkinElmer Corp. of Norwalk, Conn., it contained a 36-in. mirror that would be a respectable size even for a solid-ground observatory, but that mirror was only the beginning. The telescope was suspended so that it could swing in all directions, under precise control by ground radio. It carried a coarse-vision television camera...

Author: /time Magazine | Title: Astronomy: A Clear View of Mars | 3/15/1963 | See Source »

...United States Time Corp. of Middlebury, Conn., proudly boasts that one of its Timex watches recently swallowed by a Texas farmer's cow ran as good as new when the farmer retrieved it. Like the cow, U.S. jewelers know how it feels to swallow Timex. At first they opposed carrying Timex's low-cost, low-profit watches, but Timex is now the nation's fastest-selling timepiece. Since the first Timex was sold twelve years ago, Americans have bought 50 million of them and U.S. Time has become the world's largest watchmaker (1962 sales...

Author: /time Magazine | Title: Corporations: Watches for an Impulse | 3/15/1963 | See Source »

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