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...potential donor, en route to the hospital by ambulance from Cleveland, Texas, died of a blood clot just a few blocks away; complications prevented use of her heart. Then Dr. Robert Lennon, a Lawrence, Mass, anesthesiologist, called Cooley to say that he had a suitable donor. Mrs. Barbara Ewan, who had suffered fatal brain damage, was considered medically dead (complete absence of brain waves for a period of 48 hours) when she arrived in Houston, but her heart had been kept beating with injections of stimulants. She suffered cardiac arrest just eight blocks from the medical center...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

...artificial heart (technically known as an orthotopic cardiac prosthesis) had been developed at least partially with funds assigned to a DeBakey research team and that it had been used without adequate testing and without DeBakey's knowledge or permission. The National Heart Institute has asked DeBakey and Cooley if federal funds were used in the development of the device. If so, said Dr. Theodore Cooper, NHI's director, its use was subject to federal guidelines covering human experimentation. He explained that these guidelines stipulate that "if experiments are going to be carried out on man, every effort must...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

Some of DeBakey's associates implied that the artificial heart used by Cooley and Liotta had been developed almost entirely by DeBakey's federally funded research team. "It's the same damn heart we've been working on for years," said one of them. Though Cooley is not a member of the team, Liotta is. In this case, DeBakey's permission-and that of a special medical review board-should have been received before the heart was used...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

DeBakey, 60, a pioneering open-heart surgeon, is president of the Baylor University College of Medicine; Cooley, 49, is a member of the faculty. The two Texans have scrupulously avoided public battles, but their subordinates have been less inhibited. Those loyal to DeBakey, for example, have fostered the impression that Cooley has performed some of his 20 heart transplants prematurely. Cooley's lieutenants, on the other hand, dismiss this as professional jealousy; they point out that Cooley performed his first transplant three months before DeBakey did. DeBakey's associates also expressed concern about the purely experimental status...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

Experience Needed. Cooley, for his part, remained unruffled. He claimed that the artificial heart used in Karp was developed entirely with funds from the Texas Heart Institute and other private sources. But he was cautious in appraising its usefulness. "We have demonstrated that a mechanical device will support the body," he declared after Karp's death. "But we've got to get more experience. It can only be used in a person who is at the brink of death or in a person who has already died, as, in effect, Mr. Karp had. He was completely dependent...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

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