Word: coronaviruses
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...since faded from the headlines, obscured by rising new threats like avian influenza. But scientists know that SARS is not gone for good, and research efforts to unlock the secrets of the virus that left almost 800 dead continue. At the University of Hong Kong (HKU), where the SARS coronavirus was first identified in March 2003, researchers last week announced the results of a landmark study that could point the way toward potential anti-SARS drugs and provide a potent research tool to quickly analyze new viruses. "This is a technique that is not only applicable to SARS but also...
...SARS study, Kao and his colleagues filled the tiny wells of a small, waffle-like board with samples of the coronavirus cultured in cell lines. Microscopic amounts of different chemical compounds were introduced into each separate well using a $180,000 machine called an automated high-throughput screening platform. Once the chemicals had time to interact with the virus, scientists could examine the results with an inverted microscope. The process was repeated until all 50,240 compounds in their chemical library had been tested, which took a few months. "You'd think it'd be tedious work...
...said the discovery of the 80R antibody was a major accomplishment in international medical cooperation, coming only six months after the identification of the SARS coronavirus, in the same classification as the common cold...
...medical coordinator at the hospital, had alerted Urbani and told him the Chinese-American patient currently in the emergency ward suffering from high fever, severe muscular pains and labored breathing had possibly come down with the disease. Virologists in Hong Kong soon determined that the agent was a novel coronavirus, not a mutant flu. But Urbani, who would die of SARS on March 29, went to his grave suspecting the world was on the verge of another influenza pandemic...
...which he also sent to the Ministry of Health and the China CDC. "With winter coming, the wildlife markets have reopened, providing the perfect conditions for another outbreak of SARS," he wrote. He went on to list his findings that the civet is the major carrier of the SARS coronavirus, that the SARS coronavirus exists in different animals from different regions, that this virus can infect humans and, most frightening, that the "transmitting mechanism for the resurgence of SARS is in place." He enclosed four pages of genetic sequences taken from civets and had the letter hand-delivered...