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...poster child for the frustrations that power companies face is the proposed 600-megawatt Coyote Valley generator that Calpine Corp. wants to build in San Jose, in the heart of Silicon Valley. The facility would light 600,000 homes in a region that experienced blackouts last week, but the San Jose City Council vetoed the project in November, even though groups ranging from the Sierra Club to the N.A.A.C.P. supported it. But the plant faced opposition from Cisco Systems, the leading producer of high-speed fiber-optic networks, which happens to be San Jose's largest employer. Cisco argued that...
...Raburn, 51. "You will think about using your Eclipse almost as quickly as you use a taxi." Raburn, the son of a McDonnell Douglas engineer, started flying at 17 and later became the 18th employee hired by Microsoft. He left the company in 1982, then worked at Lotus Development Corp. and for Microsoft co-founder Paul Allen. It was when he met famed enginemaker Sam Williams in the mid-1990s that the dream for Eclipse was hatched...
...Thailand cobra, which can grow to more than 6 ft., is armed with venom that paralyzes nerves and muscles and eventually causes respiratory arrest. For the past 10 years, PhyloMed Corp., of Plantation, Fla., and the Bahamian firm Coral Pharmaceuticals have been conducting clinical trials of Immunokine, a drug derived from Thailand cobra venom, on people with multiple sclerosis. Virtually nontoxic, Immunokine seems to prevent immune cells from attacking and destroying the myelin sheath that protects nerve cells...
Each species of cone snail produces a unique venom that contains between 50 and 200 pharmacologically active peptides known as conotoxins. The most advanced conotoxin-derived drug in development is Elan Corp.'s Ziconotide, a nonaddictive treatment for severe chronic pain that is awaiting FDA approval. Cognetix, based in Salt Lake City, Utah, recently started clinical trials on a possible epilepsy treatment. Also in the works: potential therapies for schizophrenia, stroke and Parkinson's and Alzheimer's diseases...
...prod the immune system into attacking cancer cells. Clinicians have long dreamed of marshaling the body's own defenses to fight cancer, if only they could get the immune system to recognize cancer cells as easily as it spots foreign invaders such as bacteria and viruses. Researchers at Dendreon Corp. in Seattle have found a way to do just that by enlisting dendritic cells, some of the body's most potent immune stimulators...