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...drug for the first time. Azacitidine is used to treat patients with myelodysplastic syndromes (usually abbreviated, a bit oddly, to MDS), a group of rare and deadly blood malignancies. The drug uses epigenetic marks to dial down genes in blood precursor cells that have become overexpressed. According to Celgene Corp. - the Summit, N.J., company that makes azacitidine - people given a diagnosis of serious MDS live a median of two years on azacitidine; those taking conventional blood medications live just 15 months. (See 25 people who mattered...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...stitching it together," as the President put it. "Most of the organizations are built around means of collection, not means of outcomes," explains Dale Meyerrose, who served as the first intelligence community information-sharing executive under Bush, until he left government service in 2008 to join the Harris Corp., a government contractor. (Read "The Lessons of Flight...

Author: /time Magazine | Title: Obama's Terrorism Postmortem: Still Not Connecting the Dots | 1/6/2010 | See Source »

...massive amount of diesel fuel into two tributaries of China's Yellow River has exposed how far the country has to go before it can ensure the health of its imperiled waterways. An estimated 40,000 gal. (150,000 L) of diesel fuel spilled from a China National Petroleum Corp. pipeline in northwestern Shaanxi province, some two-thirds of which flowed into the Wei and Chishui rivers. Hundreds of workers have set up a series of temporary barriers in an effort to prevent the fuel from reaching the Yellow river, China's second longest waterway and a source of drinking...

Author: /time Magazine | Title: After Oil Spill, China's Polluted Rivers in Spotlight | 1/4/2010 | See Source »

...unprecedented surge in terrorism events on U.S. soil. When analysts tally these events, they refer to anything from a disrupted plot to U.S. citizens traveling abroad to seek terrorism training or a lone gunman running amok in the U.S. And by the calculations of Rand Corp. expert Brian Jenkins, more terrorist threats were uncovered in the U.S. in 2009 than in any year since...

Author: /time Magazine | Title: Domestic-Terrorism Incidents Hit a Peak in 2009 | 12/23/2009 | See Source »

...general, retailers that have focused on value, such as TJ Maxx, Kohl's Corp., Aeropostale, Children's Place, the Gap and Old Navy, have fared the best this holiday season and will likely resort to shallower discounts in the last two shopping days, says Jaffe. Best Buy, J. Crew and UrbanOutfitters have also performed well and are therefore unlikely to stray beyond planned promotions this week, he says...

Author: /time Magazine | Title: Christmas Shopping: For Retailers, Down to Two Crucial Days | 12/22/2009 | See Source »

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