Word: cortines
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...possible cause of arthritis was given last week in the Journal of the A.M.A. Dr. Hans Selye and coworkers of Montreal have found that rats get the disease if they get an overdose of desoxy-corticosterone acetate, a synthetic adrenal hormone. Dr. Selye concludes that possibly an oversupply of cortin (hormone secreted by the adrenal gland's outer husk) may be to blame for human arthritis. The adrenal glands, he says, may be stimulated by glandular imbalance (e.g., women at the menopause are very likely to get arthritis), exposure to cold, emotional shock, infections...
...patient, a middle-aged woman, was dying. She had just been brought in to the Jewish Hospital in Alexandria, Egypt. She was a victim of Addison's disease, a slow decline of the adrenal glands which cap the kidneys, gush forth the hormone cortin and the supercharging adrenalin when the nervous system signals "Emergency!" No synthetic hormones or drugs had been able to save...
Among the mechanisms that maintain the body's fluid balance are the small adrenal glands, capping the kidneys. These glands secrete several substances; one of them raises blood pressure, regulates circulation. In 1937 the adrenal hormone, known as cortin, was produced synthetically, given the bristling title desoxycorticosterone acetate. Young Pathologist David Perla of Manhattan's Montefiore Hospital decided to try it as a shock preventive. Last week, in the Proceedings of the Society for Experimental Biology and Medicine, Dr. Perla reported "excellent results...
Approach to Cortin. Dr. Harold Lawrence Mason and his associates at the Mayo Clinic in Minnesota are trying to isolate, determine the chemical structure of, and eventually synthesize the potent hormone cortin, secreted by the suprarenal glands. Cortin maintains the potassium, sodium and urea balance of the blood; without it man develops Addison's disease and dies. Last week the Mayo researchers announced isolation of a pure crystalline substance which seems to be a close cousin of cortin. The crystal molecule contains 21 atoms of carbon, 28 of hydrogen, five of oxygen. It seems to have the same effect...
...read with much interest in TIME, Aug. 12, a letter from Dr. H. Maxwell Langdon in reference to cortin and glaucoma, and holding the opposite view from that of Dr. Langdon I dash madly to the rescue of beleaguered TIME...