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...second study, Kitahata's team looked at patients who chose to start ART when their CD4 count was 500 or above and compared them with patients who decided to defer treatment until their CD4 counts dropped below 500 cells. (In a normal, healthy adult, CD4 levels range from 600 to 1,200.) In both studies, the patients deferring treatment were more likely to have died by the 2005 end of the study than were their earlier-treated cohorts. HIV-positive patients beginning therapy at CD4 levels between 351 and 500 cells were 69% more likely to be alive...
...fact, when the potent ART combination therapy first emerged in the mid-1990s, government health officials recommended that anyone with a CD4 count of 500 cells or lower receive treatment. But in response to growing concerns over HIV's increasing ability to become resistant to the drugs, as well as worries over the drugs' toxicity and patients' inconsistent compliance with their regimen, the guidelines dropped to 200 before eventually settling at 350 cells - much further along in the progression of the disease...
Malcolm Gladwell Outliers is the most recent book by the best-selling author of Blink and The Tipping Point Richard Nisbett's Intelligence and How to Get It: Why Schools and Cultures Count is a devastating and persuasive refutation of all those who believe intellectual ability is fixed at birth. Few Americans have done as much to deepen our understanding of what it means to be human...
...Menand said he is hopeful that two Gen Ed classes will count double for students’ concentrations in most cases, a stipulation that would give students more leeway than the seven-requirement Core...
...used to have trouble with offspeed pitches, but now he’s battling those off” Walsh notes. “He’s also gotten much better at fighting when he’s behind in the count. He’s figured it out, fouling off some pitches...I always felt he was on the verge of putting it together...