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...geared toward protecting consumers from potential liver damage due to unintentional overdose from the drug. According to the FDA, acetaminophen remains the leading cause of liver failure in the U.S., despite repeated government warnings. However, the majority of acetaminophen-related deaths are due to prescription drugs, not over-the-counter medications. FDA data indicate that overdoses of nonprescription cough and cold products, like NyQuil and Theraflu, occur infrequently, when patients combine these medications with other acetaminophen products, like Tylenol, and unknowingly increase their exposure to the drug. (Read "The Year in Medicine 2008: From...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...prolonged periods - especially for the treatment of chronic pain in older adults - they carry a risk of stomach ulcers and gastrointestinal bleeding. NSAIDs may also raise blood pressure and affect kidney function. If you are concerned about your acetaminophen use, ask your doctor about which over-the-counter pain remedy is best...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...still get Tylenol and other nonprescription acetaminophen products? Yes. Even if the FDA follows the committee's advice about over-the-counter acetaminophen products, they will still be available, only in lower doses...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...sleep. If taken as directed, doctors say these products are safe. At issue is the maximum daily dosage, which people may inadvertently exceed when taking a combination of medications that contain acetaminophen. Most people do not realize that the ingredient is present in so many different popular over-the-counter remedies...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...committee recommend eliminating acetaminophen-containing prescription drugs but not over-the-counter products? The members based their decision on the studies and data that were presented to them during the two-day meeting. The vast majority of studies linking liver failure to acetaminophen use involve prescription acetaminophen products, such as Vicodin or Percocet. More than 60% of the acetaminophen-associated liver problems occurred in patients using prescription medications, while only 10% occurred in those using nonprescription pain remedies. "The recommendations of the committee are based not on the logic of what we think is happening but on the data presented...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

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