Word: coxes
(lookup in dictionary)
(lookup stats)
Dates: during 1990-1999
Sort By: most recent first
(reverse)
...drug that changed Zebroski's life is just one of a new class of medications that could radically alter the way in which pain is treated in the U.S. Each year 7,600 Americans die from internal bleeding caused by long-term use of NSAIDs. The new drugs, called COX-2 inhibitors, relieve pain just about as well as aspirin and its cousins but seem to have no serious side effects. With visions of $5 billion or more in potential sales over the first five years, drug companies are racing to get their own versions of these superaspirins to market...
...1970s, researchers discovered that aspirin reduces that pain and inflammation by lowering prostaglandin levels. It does so by blocking an enzyme called cyclooxygenase, or COX, that's involved in the manufacture of prostaglandins. What scientists didn't know until the early 1990s, however, was that cyclooxygenase comes in at least two versions: COX-1, ultimately responsible for protecting the stomach and making platelets sticky; and COX-2, which triggers pain and inflammation. The obvious goal, at least as far as pain relief is concerned: develop a drug that blocks COX-2 and not COX...
...always liked him; I admired him as a student and later as another lawyer and a friend," Cox says. "He is a very warm person...
...When Cox was Watergate special prosecutor, Cox says Richardson's attitude towards him was fair...
...never overbearing about [questioning me] or exerting any kind of pressure that I thought was improper, but he had to carry out the White House's orders," Cox says...