Word: coxing
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Dates: during 2000-2009
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...could prevent the polyps from forming in the first place? In 1991 Michael Thun, an epidemiologist with the American Cancer Society, made an intriguing observation: people who regularly take aspirin are less likely to develop colorectal cancer. It turns out that aspirin blocks the production of an enzyme, called COX-2, that is found in 90% of all tumors and half of the polyps in the large intestine. Apparently most of these abnormal tissues need COX-2 to grow. Stop the production of the enzyme, and you might be able to prevent the cancer from getting larger--or from forming...
...least that's the idea. Since COX-2 is produced by normal cells as well, doctors may run into trouble if they try to shut down its production entirely. Also, taking aspirin on a regular basis can lead to other problems, like internal bleeding. Still, researchers are sufficiently intrigued by the COX-2 connection that they're trying to determine whether a new generation of seemingly safer drugs, called COX-2 inhibitors, can reduce the incidence of cancer among folks with the FAP or HNPCC genes. "It's a very exciting area of research," says Thun...
...according to some audience members, Cox and Chopra may have agreed too much...
...wish it was longer," Chopra said. "I wish we had time to really debate some of the issues a little more. But it was an opportunity to meet Harvey Cox whom I have admired for a long time...
...Cox, who has written several books including The Secular City, said he was more pleased with the discussion. "I thought it was a good dialogue," Cox reflected. "Deepak is a wonderful teacher...