Word: coxing
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Dates: during 2000-2009
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...been a painful 15 months both for people with arthritis and for the companies that make their painkilling drugs. The once high-flying anti-inflammatories known as cox-2 inhibitors nearly crashed and burned in September 2004, when Merck's popular Vioxx was pulled from the market after a study revealed it could raise the risk of heart attack and stroke. A competitor made by Pfizer, Bextra, was yanked some months later, leaving only Pfizer's Celebrex behind-and a new, required safety warning hasn't exactly done wonders for that drug's appeal. Celebrex sales are off more than...
...that Pfizer announced this week that it is going to try to settle the cox-2 safety question once and for all. Working with cardiologist Steven Nissen of the Cleveland Clinic, Pfizer has initiated a massive $100 million, four-year trial that will test the drug on 20,000 arthritis patients who are already at high risk for heart attack or stroke to determine what risk, if any, Celebrex actually poses...
...naproxen. They will also take aspirin, cholesterol-lowering drugs and other medications appropriate for heart patients, as well as a drug to prevent stomach bleeding, which all three of the painkillers may cause. The four-year study should be sufficient time to reveal what risk, if any, the cox-2s pose, but it could end sooner if one of the medications reveals itself as just too dangerous...
...current star of “Extras”) were regular contributors.You also probably haven’t heard of Daisy Donovan, another Brit who got her start as a presenter on the “Eleven O’Clock Show.” Well, thanks to Courtney Cox and David Arquette, she’s got a show all her own on TBS.It’s a sort of reality-comedy hybrid. Daisy is traveling from New York to L.A., and trying a series of careers and experiences along the way, the first being that...
...finds himself serving as filler in a "gorilla cheese sandwich"; another shows the indignant weasel on whom the kids happily daub their paintings. As the school day ends, the kids have a snack of parrot sticks and quackers, then say butterfly and get on the octopus to ride home. Cox, herself a kindergarten teacher, knows that more than contusion reigns when 4- and 5-year-olds are teased into sorting out sound-alike words. In fact, if you recognize how much verbal comprehension is conveyed by the jokes and see that Mrs. Millie is silly like...