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James Watson remembers cringing when his colleague Francis Crick announced to regulars at the Eagle, a pub in Cambridge, England, that they had discovered "the secret of life." True, the onetime ornithologist and the former physicist had created a plausible model for the structure of DNA that morning. If they were right, biologists would finally understand how parents pass characteristics on to their children--not only hair and eye color but every aspect of how the human body is built and how it operates. Watson, at left in photo, and Crick would have solved the mysteries of heredity...
...fact that double helix and Watson and Crick are familiar to just about every schoolchild, though, makes it clear that DNA was every bit as important as Crick thought. Not only did it explain heredity, but it would also lead to such practical applications as DNA forensics in law enforcement, testing for genetic diseases and the development of an entire biotechnology industry. With the recent completion of the Human Genome Project, it could radically change the way medicine is practiced over the next few decades. Crick's bold assertion was stunningly accurate. --By Michael Lemonick
...Twist Of Fate," TIME'S account of James Watson and Francis Crick's discovery of the structure of DNA, was extensive and thorough [THE DNA REVOLUTION, Feb. 17]. I am studying biology in high school, and my textbook gives the impression that Watson and Crick completely deciphered the molecule in no time flat. Learning that they made mistakes at first, as everybody else does, reignited my interest in high school biology. MICHAEL YEE Huntington Beach, Calif...
Fifty years ago this week, James Watson and Francis Crick solved the structure of DNA. To mark that momentous discovery, TIME last week convened a distinguished group of scientists, academics and business innovators for a conference in Monterey, Calif., called the Future of Life. Over three days of spirited debate, participants, including Watson, examined such issues as stem-cell research, cloning, biowarfare and nanotechnology. Near the end, Surgeon General Richard Carmona offered this piece of wisdom: "Science must take care not to leave the public behind...
...TIME president Eileen Naughton aptly predicted, these emotional topics produced fireworks. At one point, the Nobel laureate James Watson, whose discovery 50 years ago with Francis Crick of DNA?s double helix was the inspiration for the three-day talkfest, showed that even at age 74, he could be as feisty as ever. When ethicist Daniel Callahan insisted that bioscientists didn?t absolutely need embryonic stem cells in their quest to cure certain intractable ailments, Watson roared from his seat: ?That?s crap.? Stunned into momentary silence, Callahan eventually replied that maybe scientists could use them under certain circumstances...