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...quote that nailed the story, however, and put it on the front page, was the one attributed to James Watson, co-discoverer of DNA's double helix and one of the most famous scientists in the world. "Judah," he is supposed to have said, "is going to cure cancer in two years...
...Texas, who three years ago found she has non-Hodgkin's lymphoma. She has a four-year-old daughter she'd like to see grow up and a husband with whom she'd like to grow old. When friends started calling excitedly last week with news of a possible cure, she resolved to maintain a philosophical calm. "I try to live in the moment because that helps level out the emotional roller coaster," she says. Still, the moment sometimes escapes her. "I am not perfect," she says. "I am not the Dalai Lama." Ironically, it's patients like Smith...
...City, who is pursuing still another approach to anti-angiogenesis, says he doesn't need to stop tumor growth completely to judge his experiment a success: "If we can make patients with metastatic breast cancer live 20 years and not have symptoms, that may be as good as a cure...
Malkin is quick to point out that one growth-factor inhibitor isn't going to cure cancer. Cancer is a complicated disease. Tumors usually are made up of different types of cells, expressing different genes, sensitive to different growth factors and therefore responding to different drugs. "When you are trying to kill cancer cells, you're always likely to need combination treatment," says Merck's Scolnick. Like AIDS treatments, the new generation of cancer drugs will need to be combined with older drugs and possibly with one another to be most effective...
Though patients long desperately for a "cure," extending life is the more realistic goal in treating cancer. The newer drugs, unlike chemotherapy agents, are "cancer stoppers," not "cancer killers," says Malkin. Chances are that they will have to be taken for many years, or even for the rest of a patient's life. But if such drugs can slow or stop the growth and spread of malignant cells, then cancer can be transformed from an acute and deadly disease into a chronic and manageable one. That doesn't make as sexy a headline as a cancer cure...