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...become totally blind as they grow older. They have enough photoreceptor cells, but the cells don't work because one of the genes is a dud. Now Ali is firing functional versions of the faulty gene back into the photoreceptor cells, and the one-time procedure could permanently cure the blindness. Johnson's condition - a faulty RPE65 gene - is incredibly rare. But Ali says the procedure, if it works, could be used to treat any one of about 100 inherited single-gene sight disorders that, together, affect 1 in 2,000 or 3,000 people...

Author: /time Magazine | Title: A Gene to Cure Blindness | 5/18/2007 | See Source »

...field stands today. At its most basic, gene therapy is anything that introduces new genetic material to help fight or prevent a disorder. Treatment options are still in the experimental stages, and are not free of philosophical critics. But gene therapy has also been heralded as a potential cure for all kinds of genetic diseases (think cystic fibrosis or sickle-cell anemia) and even for cancer - with promising lab results to back up the hype. For that reason, gene therapy is a hive of research activity. Ali is joined by many others, at the universities of Pennsylvania, of Florida...

Author: /time Magazine | Title: A Gene to Cure Blindness | 5/18/2007 | See Source »

...LONDON: Located in a 127-year-old building overlooking verdant Hyde Park, the Mandarin Oriental London is a welcome sight for weary souls climbing out of the cab or limo from Heathrow. Its one-hour-and-50-minute Ginger Ritual ($495) is billed as the perfect jet-lag cure, and comprises deep Shiatsu massage for the kidneys, feet, hips, shoulders, neck and back, as well as aromatherapy featuring an oil that's custom-blended to a guest's needs...

Author: /time Magazine | Title: Travel Perks | 5/17/2007 | See Source »

...France and seek success abroad. France has the slowest?growing large economy in Europe, the fastest-rising public debt in western Europe over the past ten years, and its 22% youth unemployment rate is one of the highest on the continent. Sarkozy was chosen by an electorate looking to cure the malaise. Assuming he has the courage his predecessors have not had to withstand the inevitable protests and demonstrations, the President-elect will liberalize labor markets, cut taxes, relax the 35-hour-workweek laws and create more flexible contracts...

Author: /time Magazine | Title: Why the Young French Diaspora Loves Sarko | 5/9/2007 | See Source »

...helpful as beta-blockers, antidepressants and even anti-epilepsy drugs may be in preventing some migraines, they don't cure the condition. Eventually scientists hope to discover therapies that address the brain's overly sensitive circuits more directly. For what it's worth, getting older seems to soften the blow. Studies show that migraine attacks peak between the age of 35 and 45 and decline after that...

Author: /time Magazine | Title: The New Science of Headaches | 5/8/2007 | See Source »

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