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...designed to prevent the escape of potentially dangerous organisms. But there is always the chance that something or someone will fail-and that a few virulent bugs will slip through the safeguards to multiply in the outside world. Faced with this problem at the Asilomar conference. Geneticist Roy Curtiss III proposed an ingenious solution: Why not convert the standard genetic research organism, a strain of the E. coli bacterium, into a seriously weakened mutant variety that would quickly self-destruct if it escaped the laboratory? Curtiss volunteered to engineer the new bug, and his colleagues agreed to hold...

Author: /time Magazine | Title: Science: Making a Safer Microbe | 4/18/1977 | See Source »

Returning to his laboratory at the University of Alabama Medical Center in Birmingham, Curtiss quickly hit on a way to keep E. coli under control. The microbes must be able to manufacture a protective membrane; without such an outer coat they would swell and burst during normal growth. To keep them from manufacturing a complete coat, Curtiss created an E. coli with a defect in a gene that makes diaminopimelic acid (DAP), an important ingredient of the membrane. The defect made the bugs dependent for their survival upon DAP supplied by scientists...

Author: /time Magazine | Title: Science: Making a Safer Microbe | 4/18/1977 | See Source »

...already revving up to cut themselves in on the profits. Except for General Motors, which in 1970 bought a license to make Wankels in a deal that will eventually cost it $50 million, any manufacturer who decides to build a rotary engine will presumably have to pay royalties to Curtiss-Wright Corp., which owns North American patent rights to the design. Largely on the strength of that asset, Curtiss-Wright stock shot up from 1 ⅜ to 59 ¼ earlier this year, though it has settled back in recent weeks to around 45. Officers of machine tool firms are hoping...

Author: /time Magazine | Title: AUTOS: Revving Up for the Wankel | 8/14/1972 | See Source »

...four and my most vivid recollection of the event was my impression of the airplane as I first saw it from our upstairs dining-room window. The Curtiss pusher type, with its framework fuselage, looked from sideview exactly like a giant safety...

Author: /time Magazine | Title: Letters, Jan. 11, 1971 | 1/11/1971 | See Source »

Died. Alfred V. Verville, 79, pioneer aircraft designer who in 1914 with Glenn Curtiss designed the famed Curtiss Jenny, and later as a U.S. Army Air Service engineer developed the nation's first welded-fuselage fighter plane with droppable fuel tanks, the PW-1 Pursuit; of a heart attack; in La Jolla, Calif...

Author: /time Magazine | Title: Milestones: Mar. 23, 1970 | 3/23/1970 | See Source »

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