Word: cutters
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...specific reason has yet been found to explain why two lots of vaccine made by California's Cutter Laboratories should have touched off polio infections in so many cases (69 at week's end), but Dr. Sebrell went...
From all sides he had heard manufacturers report failures "for no apparent reason" in the process of inactivating the virus, i.e., making a safe vaccine. A manufacturing rival of Cutter said with commendable candor: "There is absolutely nothing to indicate that Cutter testing was not adequate. If that's so, then what happened to them could have happened...
Tenfold Step-Up. While these disclosures were being made as unobtrusively as possible, PHS officials succeeded in beating down opposition by some of the vaccine makers so that all eventually accepted amendments to the testing procedures. (If Cutter makes and tests vaccine according to the revised specifications, it can get back into the business.) Spokesmen for both sides had been chattering all week about the new procedures being simply a question of interpretation-as Dr. Jonas E. Salk put it, "like reading the fine print in an insurance policy." But this was not so. The changes, as finally announced, were...
...original "safe" vaccine had been followed by 113 cases of polio among the vaccinated. Last week an additional ten were among Cutter subjects. But because four full weeks had passed since Cutter inoculations were stopped, and the incubation period for polio is rarely more than 31 days, it seemed more likely that in the new Cutter cases the trouble was not defective vaccine, but the absence of a second shot in time to prevent a natural polio infection...
Getting Under the Skin? More startling and possibly just as significant, though no epidemiologist wanted to commit himself, was the fact that 23 cases had developed in the families of children who had come down with polio after getting Cutter vaccine. Eleven were adults, and one had died. This was a notably higher rate for family contact cases than would be expected, or than had been seen in last year's trials...