Word: cyclo
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Dates: during 2000-2009
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Sometimes the reason for the initial inflammatory cycle is obvious - as with chronic heartburn, which continually bathes the lining of the esophagus with stomach acid, predisposing a person to esophageal cancer. Other times, it's less clear. Scientists are exploring the role of an enzyme called cyclo-oxygenase 2 (COX-2) in the development of colon cancer. COX-2 is yet another protein produced by the body during inflammation...
...also not clear exactly how aspirin works to ward off polyps. There is evidence to suggest that it slows down the enzyme known as cyclo-oxygenase 2, or COX-2, which seems to play a role in spurring cell growth that can lead to tumors. But for reasons no one can yet explain, higher doses of aspirin didn't translate into more protection. In one of the studies reported last week, more patients in the group taking full-strength, 325-mg aspirin pills developed colon cancer (10.7%) than in the group taking so-called baby, or 81-mg, aspirin...
...featuring homes with verandas and an array of picturesque churches and mosques. There are fewer than 200 homes inside the fort, and in the past several years adventurous foreigners have purchased more than 40 of them. In many parts of the tropics, tourists are accustomed to being accosted by cyclo-drivers hawking all sorts of illegal temptations. In the fort, though, the inevitable refrain is, "Mister, you like to buy a nice house...
...Doyle behind the camera?had to drift back to Vietnam. Again there were white men giving orders to yellow men, car bombs in a Saigon square, dangerous assignations in the jungle. The crew shut down Ho Chi Minh City's busiest square for a week, transforming it into the cyclo-filled Saigon of colonial days. They did the same a month later in Hanoi's Old Quarter, and then the 1,000-year-old city of Hoi An. This time, no one was killed, but all that heavy machinery threatened to sabotage a complex vision. In cinema...
...inhibitors hit the market in 1999, doctors and patients alike expected a lot from the little painkillers. The old standbys--which include aspirin and ibuprofen (Advil)--can tear up the lining of the stomach and cause serious bleeding disorders. These side effects occur when a protective enzyme called cyclo-oxygenase 1, or COX-1, is suppressed. Because the COX-2 inhibitors don't affect COX-1, it was expected that they would have fewer side effects...