Word: cypa
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...gene, TRIM5-CypA, produces a protein that is a fusion between two existing proteins—TRIM5 and CypA. TRIM5 binds to viruses related to HIV and destroys them while viruses use the CypA protein to shield themselves from the host cell, said Medical School professor Shawn P. O’Neil, one of the authors of the study...
Because the CypA protein attracts HIV-like viruses and the TRIM5 protein destroys them, the fused protein “might be able to target lentiviruses...
While looking at the natural variation in the TRIM5 gene in Asian macaques, which are considered Old World monkeys, Harvard microbiologist Ruchi M. Newman accidentally discovered a second example of the TRIM5-CypA fusion, according to Medical School professor Welkin P. Johnson, the study’s senior author...
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