Word: cystic
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...other institution houses as many biomedical researchers on a single campus. "It's the linchpin of biomedical research," says Yale medical school dean Leon Rosenberg. Last year alone, NIH scientists or their associates on university campuses began the first federally sanctioned gene therapy on a human, located the cystic fibrosis gene, developed a drug to reduce paralysis from spinal-cord injuries and demonstrated that the drug AZT prolongs life in AIDS patients...
...just found the gene for neurofibromatosis, often confused with Elephant Man's disease. A year ago, you were instrumental in finding the gene that triggers cystic fibrosis. How will such discoveries affect the practice of medicine...
...adds a sense of urgency. The cystic fibrosis gene has been found now for a year, and in that year 1,000 people have died, including people I knew personally. That is both troubling and motivating. You can't sit back and treat what you do as an intellectual exercise when the mere mention of a disease brings to your mind the faces of people you care about. That's why it's important to have a certain percentage of people working in this field who are comfortable with both basic science and clinical medicine...
...people were found to be sickle-cell carriers, with no significant risk to their own health, but they wound up believing that eventually they would become ill. Insurers canceled policies. It is terrifying to look back on this experience, and a good reason to go slow on screening for cystic fibrosis...
...sperm and implanting resulting embryos in the mother's womb. The main difficulty is that only one in ten tries results in a birth. Yet the success rate may improve, and prefertilization diagnosis could someday be used to intercept defective genes that cause such diseases as Tay-Sachs, cystic fibrosis and thalassemia...