Word: daraprim
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Ardery says: "You probably won't get sick in Africa (I never did), but if you do, the disease might be debilitating or fatal, so in addition to the standard inoculations, get cholera shots and buy an anti-malaria drug like chioroquine or Daraprim...
...chloroquine and 45 mg. of another antimalarial known as primaquine. If they develop malaria despite this, they are likely to be infected by a resistant strain of parasites. If massive doses of chloroquine fail to bring the fever down within a few hours, the medics may switch to pyrimethamine (Daraprim), which is effective in some of the less severe cases. In most instances, however, the medics are forced back to quinine, the oldest antimalarial of all. For pernicious malaria threatening the brain, quinine must be given intravenously in heavy doses, which may in itself cause death...
...they do any good, the improvement should be most obvious in acute cases. But because toxoplasmosis is hard to identify, the patient often does not get the treatment soon enough. Last week Microbiologist Don E. Eyles of the National Institutes of Health reported a hopeful new lead: Daraprim, which has already shown promise against the protozoa of malaria (TIME, Sept. 1), is effective against toxoplasmosis in mice when given with sulfadiazine. Now the trick is to extend the benefits from mice...
...Indian doctors report great success in treating fever relapses with a single dose of inexpensive Camoquin; they have also found that later relapses are few, and spaced farther apart. U.S., British and Belgian researchers are hard at work testing yet another new drug, daraprim. A thousand times as powerful as quinine, it can be taken in tiny, tasteless doses, and newborn Negro babies in Africa show no ill effects. So far, varying results with daraprim reflect the protean nature of malaria itself...
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