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When foods like turkey, bread and caramel are heated, proteins bind with sugars, causing the surface to darken and, in some cases, turn soft and sticky. In the 1970s, biochemists hypothesized that the same reaction might occur in the bodies of people suffering from diabetes, as excess glucose combined with proteins in the course of metabolism. When sugars and proteins bond, they attract other proteins, which form a sticky, weblike network that could stiffen joints, block arteries and cloud clear tissues like the lens of the eye, leading to cataracts. Since diabetics suffer from all these ailments, the biochemists guessed...

Author: /time Magazine | Title: CAN WE STAY YOUNG? | 11/25/1996 | See Source »

...being here and denying the pain that was now an insoluble fact. To continue with the Games in the shadow of death was to hold a party where everyone wore black. Yet to give up on the Centennial Olympics was to concede victory to the very forces that would darken us. The city was stuck like a runaway in a tunnel of fire...

Author: /time Magazine | Title: LOST MAGIC | 8/5/1996 | See Source »

...Steve Martins isn't just anyone. For him, 1994-1995 did not live up to expectations. The team's tough campaign and first-round ECAC playoff loss darken any individual success he might have...

Author: By Jonathan Finer, | Title: Martins, Butler: Two Seniors, Two Teams, Two Leaders | 6/8/1995 | See Source »

Such concerns have helped darken the outlook for executives like Stafford. Instead of the strong earnings she once expected, Stafford looks for profits at her company to be "stagnant or slightly down this year.'' Meanwhile, she is keeping her expansion plans on hold for at least six to nine months. She may know by then whether Greenspan has indeed trimmed growth by the amount he intended-or sent the recovery packing...

Author: /time Magazine | Title: THAT SINKING FEELING | 2/6/1995 | See Source »

...assembling such a wonderful cast of grim supporting characters, Soderbergh allows Bradford to shine even more. Spalding Gray as a suicidal ex-millionaire and Elizabeth McGovern as a bitter and jaded prostitute darken the tone and mood of every scene they are in, giving the second half of the film an eerily acerbic edge. Also featured is the underrated Karen Allen as Aaron's (almost overly) benevolent teacher...

Author: By Ariel Foxman, | Title: Home Alone, for Real | 10/14/1993 | See Source »

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