Word: debakey
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...touched off an angry controversy over the wisdom of trying out the device without further experimentation. It also brought into the open a feud that has long simmered between two noted surgeons: Dr. Denton A. Cooley, who implanted the mechanical heart in Karp, and the equally famous Dr.Michael E. DeBakey...
Even before Karp died, rumors began surfacing that the artificial heart (technically known as an orthotopic cardiac prosthesis) had been developed at least partially with funds assigned to a DeBakey research team and that it had been used without adequate testing and without DeBakey's knowledge or permission. The National Heart Institute has asked DeBakey and Cooley if federal funds were used in the development of the device. If so, said Dr. Theodore Cooper, NHI's director, its use was subject to federal guidelines covering human experimentation. He explained that these guidelines stipulate that "if experiments are going...
...Some of DeBakey's associates implied that the artificial heart used by Cooley and Liotta had been developed almost entirely by DeBakey's federally funded research team. "It's the same damn heart we've been working on for years," said one of them. Though Cooley is not a member of the team, Liotta is. In this case, DeBakey's permission-and that of a special medical review board-should have been received before the heart was used...
...DeBakey, 60, a pioneering open-heart surgeon, is president of the Baylor University College of Medicine; Cooley, 49, is a member of the faculty. The two Texans have scrupulously avoided public battles, but their subordinates have been less inhibited. Those loyal to DeBakey, for example, have fostered the impression that Cooley has performed some of his 20 heart transplants prematurely. Cooley's lieutenants, on the other hand, dismiss this as professional jealousy; they point out that Cooley performed his first transplant three months before DeBakey did. DeBakey's associates also expressed concern about the purely experimental status...
...Efforts to find an animal source of transplantable hearts are not likely to succeed before the artificial heart is perfected, according to DeBakey. The first heart transplanted into a human being was a chimpanzee's in 1964, and it failed. This year, a sheep's heart also failed. The great apes are too scarce, and too reluctant to breed in captivity to be a source of supply. Before animals' hearts can escape rejection, researchers will have to outwit the genetic code and raise special breeds-a matter of years...