Word: defect
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Dates: during 1990-1999
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Hata's new party, roughly translated as Japan Renewal, the second group in three days to defect from the Liberal Democrats, is considered the most likely to pull together a coalition able to oust what is left of Japan's unruly and unroyal dynasty. Once the managers of Japan's rise to economic-superpower status under the warm glow of its alliance with the U.S., the Liberal Democrats today are noted for a single, sordid attribute: corruption. Prime Minister Kiichi Miyazawa sank to a lowly 9% approval rating two weeks ago after he buckled under party pressure and failed...
Throughout the year, Medical School Professor of Genetics James F. Gusella and his colleagues at the MGH Molecular Neurogenetics Unit reported several "candidate" genes for the defect which causes Huntington's Disease, the usually fatal neurodegenerative disorder which killed folk singer Woody Guthrie...
Finally, in the March 26 issue of Cell, Gusella, who in 1983 discovered the general location of the defective sequence, announced that he and researchers from 10 other institutions around the globe had identified the defect...
...discovery of the defect, a "genetic stutter" of three nucleotides, the basepairs which make up DNA, should make possible a quicker and more inexpensive test for the disease, and eventually a better understanding of the mechanism which kills brain cells in the approximately 25,000 U.S. Huntington's patients...
24After a frantic search lasting more than a decade, harvard Medical School researchers report that they have located the elushe genetic defect responsible for Huntington's disease." The Key to the defect is a short repeated sequence of DNA, Just three base pairs of the millions which make up each Human chromosome. With the finding, a quicker and more inexpensive test for the degenerative disease of the central network system, and eventually a better understanding of the disease mechanism, may feed to a cure...