Word: defect
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Dates: during 1990-1999
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...newly discovered defect does not in itself produce cancer in the way that an inherited defect causes cystic fibrosis or sickle-cell anemia. "What the mutant gene does is create a predisposition to cancer," Vogelstein explains. "And it's only with additional mutations after birth that the cancer will appear...
Jean-Mark Lalouel, a co-author of the study and professor of human genetics at the University of Utah, last week called the findings only a first step, saying the gene defect may eventually aid in early diagnosis and treatment...
Pregnancy brings about major physiological changes and it is possible that these changes reveal "the underlying differences" between those who develop preeclampsia and those who do not, Lalouel said, among those who inherit the preeclampsia genetic defect...
...some questions remain, according to Williams. Last year, the same research group demonstrated an association of the same gene defect with normal hypertension. Why, he asked, are preeclamptic women not prone to develop normal hypertension later in life...
...voted not to support a contract extension. This caused some members of the CCA who supported Healy's contract to defect to the Cambridge Alliance. Winters, a former member of the board of directors of the CCA, has said that he was asked to leave the CCA because he supported Healy's contract...