Word: defect
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Dates: during 1990-1999
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...much dicier showdown, however, is coming this week, when the Senate takes up Clinton's plan for a quick $16 billion spending stimulus to the economy. Again it faces solid Republican opposition (though probably not a filibuster), and this time more conservative Democrats may defect. Clinton planned to get on the telephone to waverers, and his bill probably will pass in some form. But without weakening amendments? Stay tuned...
...defect is a short repeated sequence of DNA, just three base pairs of the millions which make up each human chromosome. With the finding, a quicker and more inexpensive test for the devastating degenerative disease of the central nervous system, and eventually a better understanding of the disease mechanism, may lead to a cure...
James F. Gusella, professor of genetics and a leading collaborator in the 10-institution search, said in a telephone interview yesterday he felt "great relief" upon discovering the defect responsible for the usually fatal disease, which killed folksinger Woody Guthrie...
...opens possibilities for taking the defect of the disease that causes cell death and having the pathway worked out for steps to target for treatment," said Gusella, who nine years ago discovered the general location of the defective sequence...
Hayden reports this week of a different candidate for the genetic defect, which may have a regulatory effect on Gusella's find, and emphasized that much more work still needs to be done...