Word: defective
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Dates: during 1930-1939
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...Andrews is able to favor industry with such advisory opinions only by straining the Act. Nowhere does it authorize him to issue general regulations and interim interpretations to serve until the U. S. Supreme Court has spoken. This defect in the Act may be corrected by amendment when Congress convenes in January...
Their importance to science is that they have a unique hereditary defect of the sort which crops out occasionally in nature but which human investigators cannot produce at will. Some disturbance in the rat chromosomes (heredity carriers in the germ plasm) prevents their soft, prenatal cartilage from developing into a normal skeleton. The young appear normal for two weeks, then become bandy-legged as if suffering from rickets. Usually they die at the age of four to five weeks, with soft, collapsed ribs and emphysema of the lungs (air leakage into the spaces of the connective tissue...
...strain can be perpetuated because, according to the Mendelian three-to-one ratio, only one in four of the young rats manifests the lethal defect. Four of the females littered last week, and the colony now numbers about 30. Since zoologists by studying such anomalies can cast more light on the mystery of heredity transmission in the chromosomes, several U. S. scientists have expressed great interest in Dr. Dunn's new boarders. He plans soon to ship specimens to other laboratories...
Last year, long before the recent war scare, Dr. Dunn received from England a consignment of mice with a hereditary defect. Their teeth grew backward into their jaws, causing early death from malnutrition. Reason for this shipment was the same: fear of destruction by bombs...
...other hand it was shown that those who have exhibited a strong determination to conquer this defect have through regular and consistent efforts achieved success...