Word: dementia
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...been pointed out that the total number of A. beta deposits show only a modest correlation with degree of dementia," Selkoe writes in a recent Science Magazine article. "But this is precisely what one would expect from an initiating factor...
...plaque clusters around degenerating nerve endings during the early stages of the disease. However, numerous other cellular changes must take place to degenerate the nerve endings, thus leading to true dementia, he says...
...earliest AIDS deaths were accompanied by roaring panic. My friend Eric, a stage manager and haberdashery salesclerk, died in '86. His extreme weight loss and hollow-cheeked pallor gave him a look of near theatrical decay, and his paranoia and memory loss were not then recognized as symptoms of dementia. He was surprisingly granted a luxurious room in a Manhattan hospital, with a uniformed guard at the door; we later discovered that the staff was being extra cautious because another AIDS patient had jumped from the roof a day earlier. All visitors were required to wear surgical masks, but almost...
...utterly deranged. Given the chance to indulge herself by playing such a comically evil figure, Glenn Close delivers a masterful and unrestrained performance. Close gets to verbally abuse every character in the movie, shouting her insults with contempt and devilish glee. She also perfects the look of materialistic dementia that defines Cruella's character. Because the puppies are real, rather than animated, De Vil's desire to turn them into an extravagant possession seems all the more depraved...
...been updated to the nineties, so that Cruella is a fashion mogul with a large corporation and Roger designs video games. In the movie, Roger is working on a game featuring Dalmatians, but he cannot find the perfect villain for his creation until he meets De Vil, whose dementia serves as a twisted inspiration...