Word: designations
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Dates: during 1990-1999
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Structure-based Drug Design: Using the digital three-dimensional structure of a target molecule to "reverse-engineer" a drug candidate...
...many consider the less than 30-year old biotechnology industry to be still in its nascent stages. The recent advent of countless new technologies such as bioinformatics, structure-based drug design, combinatorial chemistry and high throughput screening has resulted in cutting-edge technologies and novel biomedical products that are being introduced into the market...
Vertex, founded by a Harvard graduate in 1989, is a pioneer in "structure-based drug design." In theory, the idea is plausible enough: if one knows the precise three-dimensional structure of an enzyme target, one can use a computer to design a perfectly complementary "small molecule drug" to jam into the enzyme and disable it, just as a locksmith can build a key from scratch to open a lock...
...recently read the article "The 7 Best Web Sites@Harvard" in the Science and Technology section (Apr. 7). In choosing the "best" web sites, the writer, Scott A. Penner, seemed to focus on design, organization, and usefulness in the sense that someone might use this site as a reference source to get information for a paper...
...been no significant change in our human DNA. But over the next hundred years, we will be able and tempted to tinker. No doubt we'll make some improvements and some mistakes. We'll encode our dreams and vanities and hubris. We'll clone ourselves, we'll custom-design our kids. By playing Dr. Frankenstein, we'll have the chance to make miracles or monsters. The challenges will be not scientific but moral...