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...they aren't used to prevent swine flu, can they help slow the spread of a pandemic? The most effective way of slowing a pandemic is to develop a vaccine. But doing so can take months. In the interim, antivirals may play a vital roll by making ill patients less contagious. When a person is sick with the flu, he or she "sheds" virus through coughing, sneezing and other excretions. Effective antivirals lessen the amount of virus a patient sheds (because the patient is not as severely ill) and shortens the length of time he or she sheds virus...

Author: /time Magazine | Title: Q&A: How Antivirals Can Save Lives | 4/29/2009 | See Source »

...also happen spontaneously: during this winter's flu season, when antivirals were not widely used, the dominant strain of influenza suddenly became resistant to Oseltamivir. Doctors are uncertain as to why. In a pandemic situation, when the drugs will be widely prescribed, many virologists believe that resistance will inevitably develop - they just hope it will happen slowly...

Author: /time Magazine | Title: Q&A: How Antivirals Can Save Lives | 4/29/2009 | See Source »

...vaccine may also prove easier to develop since all it requires is an accurate genetic sequence of three critical virus genes. That could especially help with swine flu, since researchers found back in the 1970s that the virus doesn't grow well in chicken eggs; that could slash the yield and slow production of a potential new vaccine. "As long as we get the genetic sequence of some viral proteins, it doesn't matter where the virus came from - human, swine or bird," says Singhvi. So far, Novavax's shot is still in the testing phase, but its VLP-based...

Author: /time Magazine | Title: How Fast Could a Swine Flu Vaccine Be Produced? | 4/29/2009 | See Source »

...made and maintained ... particularly in the frontal lobe" says Geraldine Dawson, chief science officer for Autism Speaks, an advocacy group that, along with the National Institutes of Health, funds the AGRE database. The hope, says Dawson, a co-author of the two Nature papers, is that researchers could ultimately develop drugs that affect the biochemical pathways associated with these genes. Drugs that are precisely targeted in this way are already being tested in an autism-related disorder called Fragile X syndrome. Even if there are hundreds of genetic combinations that lead to autism, there may be common pathways for drugmakers...

Author: /time Magazine | Title: Autism Linked to Genes That Govern How the Brain Is Wired | 4/28/2009 | See Source »

Though Correa has cajoled oil companies to hand over a bigger share of revenue to the government and pressured banks to cut interest rates, Ecuador - unlike Venezuela and Bolivia - hasn't nationalized industries. Indeed, Correa does not shy from development that irks his presumed base of support. A workaholic micromanager who peppers his ministers with cell-phone calls, Correa backed new legislation designed to develop untouched deposits of gold and copper, angering indigenous groups and environmentalists. Communists rail against his introduction of testing of public-school teachers. "Correa isn't stupid," says analyst Margarita Andrade at Analytica Investments in Quito...

Author: /time Magazine | Title: In Ecuador, a Win for the Left May Be Good for Business | 4/28/2009 | See Source »

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