Word: dicoumarin
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Dates: during 1942-1942
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Sweet Clover. The remarkable drug known as dicoumarin may even reduce to zero the 6% of post-operative deaths caused by thrombi (fixed blood clots) and emboli (wandering blood clots). Dicoumarin is found in spoiled sweet clover, was originally tracked down as a poison which causes hemorrhages in cows, is now synthesized...
...Dicoumarin, just as effective as heparin, is far cheaper and may be given by mouth. Dr. Silbert predicted that dicoumarin will soon be used not only as a cure for thrombi, but as a routine preventive in all major operations and confinements. At present it is used in the Mayo Clinic, the University of Wisconsin, and by Drs. Irving Sherwood Wright and Andrew Gabriel Prandoni of Columbia, who made a technical report on it last fortnight...